Neuroprotective agents in severe head injury.
نویسنده
چکیده
منابع مشابه
Neuroprotective Effects of Berberine After Severe Traumatic Brain Injury in Male Rats: The Role of IL-1β and IL 10
Background and purpose: Traumatic brain injury (TBI) is the leading cause of death in young people. Berberine is a flavonoid rich in barberries and many traditional Iranian herbal remedies that could be used in treatment of neurodegenerative diseases. These properties make it a viable treatment for neurodegenerative diseases. Therefore, this study intended to investigate the neuroprotective ac...
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Background and purpose: Allicin has a wide range of pharmacological functions, all of which can be demonstrated in anti-inflammatory, antioxidant, antifungal and anti-tumor activities. In this research, we investigated the neuroprotective role of allicin in the process of diffuse traumatic brain injury and its effect on interleukin levels and histological changes in rats. Materials and method...
متن کاملUse of lidocaine and fentanyl premedication for neuroprotective rapid sequence intubation in the emergency department.
INTRODUCTION Autoregulation is dysfunctional in the injured brain. Increases in intracranial and arterial pressure may therefore result in extension of the primary injury. Rapid sequence intubation (RSI) is a well-known cause of surges in both arterial pressure and intracranial pressure. Neuroprotective agents, namely lidocaine and fentanyl, have the potential to minimize the pressure surges im...
متن کاملSynthes Award For Resident Research On Craniofacial And Brain Injury: effect of cyclosporin A, topiramate, or 100% oxygen as proposed "neuroprotective" therapies on the neurochemical analytes in patients with severe traumatic brain injury.
INTRODUCTION Three separate phase II, mechanistic, clinical have trials recently evaluated the biological and “neuroprotective” effects of Cyclosporin A,14,15 topiramate,3 and 100% oxygen17 in patients with severe traumatic brain injury (TBI). The current study is a combined analysis of these three trials, and a direct comparison of the effect of these three drugs on the local brain neurochemis...
متن کاملNeuroprotective effects of gallic acid in a rat model of traumatic brain injury: behavioral, electrophysiological and molecular studies
Objective(s): Traumatic brain injury (TBI) is one of the main causes of intellectual and cognitive disabilities. Clinically, it is essential to limit the development of cognitive impairment after TBI. In the present study, the neuroprotective effects of gallic acid (GA) on neurological score, memory, long-term potentiation (LTP) from hippocampal dentate gyrus (hDG), brain lipid peroxidation an...
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ورودعنوان ژورنال:
- Clinical and experimental pharmacology & physiology
دوره 23 8 شماره
صفحات -
تاریخ انتشار 1996